Topological classification of RNA structures.

  title={Topological classification of RNA structures.},
  author={Michael Bon and G. Vernizzi and Henri Orland and A. Zee},
  journal={Journal of molecular biology},
  volume={379 4},
We present a novel topological classification of RNA secondary structures with pseudoknots. It is based on the topological genus of the circular diagram associated to the RNA base-pair structure. The genus is a positive integer number whose value quantifies the topological complexity of the folded RNA structure. In such a representation, planar diagrams correspond to pure RNA secondary structures and have zero genus, whereas non-planar diagrams correspond to pseudoknotted structures and have… CONTINUE READING