Topological Flow Structures in a Mathematical Model for Rotation-Mediated Cell Aggregation

  title={Topological Flow Structures in a Mathematical Model for Rotation-Mediated Cell Aggregation},
  author={Alexander Wiebel and Raymond Chan and Christina Wolf and Andrea Robitzki and Angela Stevens and Gerik Scheuermann},
In this paper we apply vector field topology methods to a mathematical model for the fluid dynamics of reaggregation processes in tissue engineering. The experimental background are dispersed embryonic retinal cells, which reaggregate in a rotation culture on a gyratory shaker, according to defined rotation and culture conditions. Under optimal conditions, finally complex 3D spheres result. In order to optimize high throughput drug testing systems of biological cell and tissue models, a major… CONTINUE READING
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A Biofluid Dynamic Model for Centrifugal Accelerated Cell Culture Systems. PhD thesis, Fakultät für Mathematik und Informatik, Universität Leizig, DFG-Graduate College InterNeuro

  • Raymond Chan
  • 2008
1 Excerpt

Flow around an impulsively arrested circular cylinder

  • G. J. Sheard, T. Leweke, M. C. Thompson, K. Hourigan
  • Physics of Fluids,
  • 2007
1 Excerpt

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