Topoisomerase 2α and thymidylate synthase expression in adrenocortical cancer.


Topoisomerase II alpha (TOP2A) and thymidylate synthase (TS) are known prognostic parameters in several tumors and also predictors of efficacy of anthracyclines, topoisomerase inhibitors and fluoropirimidines, respectively. Expression of TOP2A and TS mRNA was assessed in 98 patients with adrenocortical carcinoma (ACC) and protein expression was assessed by… (More)
DOI: 10.1530/ERC-17-0095

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@article{Roca2017Topoisomerase2A, title={Topoisomerase 2α and thymidylate synthase expression in adrenocortical cancer.}, author={Elisa Roca and Alfredo Berruti and Silviu Sbiera and Ida Rapa and Ester Oneda and Paola Sperone and Cristina Lucia Ronchi and Laura Ferrari and Salvatore Grisanti and Antonina Germano and Barbara Zaggia and Giorgio Vittorio Scagliotti and Martin Fassnacht and Marco Volante and Massimo Terzolo and Mauro Giulio Papotti}, journal={Endocrine-related cancer}, year={2017}, volume={24 7}, pages={299-307} }