Topography of the sleep/wake states related EEG microstructure and transitions structure differentiates the functionally distinct cholinergic innervation disorders in rat.

@article{Petrovi2013TopographyOT,
  title={Topography of the sleep/wake states related EEG microstructure and transitions structure differentiates the functionally distinct cholinergic innervation disorders in rat.},
  author={Jelena Petrovi{\'c} and Katarina Lazic and Jelena Ciric and A. Kalauzi and Jasna Saponjic},
  journal={Behavioural brain research},
  year={2013},
  volume={256},
  pages={108-18}
}
In order to identify the differences for the onset and progression of functionally distinct cholinergic innervation disorders, we investigated the effect of bilateral nucleus basalis (NB) and pedunculopontine tegmental nucleus (PPT) lesions on sleep/wake states and electroencephalographic (EEG) microstructure in rats, chronically implanted for sleep recording. Bilateral NB lesion transiently altered Wake/NREM duration within the sensorimotor cortex, and Wake/REM duration within the motor cortex… CONTINUE READING