Topography of the human corpus callosum revisited—Comprehensive fiber tractography using diffusion tensor magnetic resonance imaging

@article{Hofer2006TopographyOT,
  title={Topography of the human corpus callosum revisited—Comprehensive fiber tractography using diffusion tensor magnetic resonance imaging},
  author={Sabine Hofer and Jens Frahm},
  journal={NeuroImage},
  year={2006},
  volume={32},
  pages={989-994}
}
  • S. Hofer, J. Frahm
  • Published 1 September 2006
  • Computer Science, Psychology, Medicine
  • NeuroImage
Several tracing studies have established a topographical distribution of fiber connections to the cortex in midsagittal cross-sections of the corpus callosum (CC). The most prominent example is Witelson's scheme, which defines five vertical partitions mainly based on primate data. Conventional MRI of the human CC does not reveal morphologically discernable structures, although microscopy techniques identified myelinated axons with a relatively small diameter in the anterior and posterior third… 
Review of Corpus Callosum Topography, Analysis of Diffusion Values for the Different Callosal Fibers and Sex Differences
TLDR
It is found that motor fibers occupy a much larger portion of the corpus callosum than previously believed on the basis of anatomical data and provides evidence for the role of DTI, which reaches beyond the information given by morphological analysis.
Single-shot T1 mapping of the corpus callosum: a rapid characterization of fiber bundle anatomy
Using diffusion-tensor magnetic resonance imaging and fiber tractography the topographic organization of the human corpus callosum (CC) has been described to comprise five segments with fibers
Segmentation of the canine corpus callosum using diffusion-tensor imaging tractography.
TLDR
Using six cortical ROIs, functional white matter connections passing through the canine corpus callosum are identified that reflect major functional divisions of the cerebral hemispheres and derived quantitative values that can be used for study of canine models of human WM pathologic states.
Probabilistic topography of human corpus callosum using cytoarchitectural parcellation and high angular resolution diffusion imaging tractography
TLDR
This sophisticated topography of the corpus callosum is the first topographic subdivisions of the CC done using HARDI tractography and cytoarchitectonic information and may serve as a landmark to further understand the correlations between the CC, brain intercommunication, and functional cy toarchitectures.
Topography of the Chimpanzee Corpus Callosum
TLDR
The results indicate chimpanzees display similar topography of the CC as humans, in terms of distribution of callosal projections and microstructure of fibers as determined by anisotropy measures.
New insights in the homotopic and heterotopic connectivity of the frontal portion of the human corpus callosum revealed by microdissection and diffusion tractography
TLDR
A novel microdissection approach was adopted, to expose the frontal fibers of CC from the dorsum to the lateral cortex in eight hemispheres and in one entire brain, thus clarifying the functional role of the CC in mediating the inter‐hemispheric connectivity.
Altered white matter microstructure in the corpus callosum in Huntington's disease: Implications for cortical “disconnection”
TLDR
Evidence is provided for early degeneration of commissural pyramidal neurons in the neocortex, loss of cortico-cortical connectivity, and functional compromise of associative cortical processing in Huntington's disease subjects.
Human Motor Corpus Callosum: Topography, Somatotopy, and Link between Microstructure and Function
TLDR
It is demonstrated that CMFs connecting defined body representations of M1 map onto a circumscribed region in the CC in a somatotopically organized manner, and the significant and topographically specific positive correlation between FA and interhemispheric inhibition strongly suggests that microstructure can be directly linked to functional connectivity.
An Analysis Method of the Fiber Tractography of Corpus Callosum in Autism Based on Diffusion Tensor Imaging Data
  • X. Ke, Shan-shan Hong, +5 authors Zuhong Lu
  • Computer Science
    2008 2nd International Conference on Bioinformatics and Biomedical Engineering
  • 2008
TLDR
DTI-based region-of-interest (ROI) fiber tractography of the entire corpus callosum and subregions provide a comprehensive and comparable method to study the white matter organization, particularly applied in autism.
High-resolution imaging of distinct human corpus callosum microstructure and topography of structural connectivity to cortices at high field
TLDR
The findings indicate that high-resolution T1 relaxometry imaging could provide a complementary and robust neuroimaging tool, useful for exploring the complex tissue properties and topographic organization of the human corpus callosum.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 29 REFERENCES
Functional organization of human occipital-callosal fiber tracts.
TLDR
It is concluded that most of the estimated tracts are real and can be localized with a precision of 1-2 mm, but many tracts are missed because of data and algorithm limitations.
DTI tractography based parcellation of white matter: Application to the mid-sagittal morphology of corpus callosum
Morphology of the corpus callosum (CC) at the mid-sagittal level has been a target of extensive studies. However, the lack of internal structures and its polymorphism make it a challenging task to
Diffusion anisotropy in the corpus callosum.
TLDR
The results of this investigation show a statistically significant increase in anisotropy of the corpus callosum in its more posterior portions compared with its more anterior portions across sex and age groups.
Topography of the Human Corpus Callosum
TLDR
The topographical organization of fibers in the human corpus callosum appears to be fairly similar to that found in the rhesus monkey (Macaca mulatta).
Regional MRI measurements of the corpus callosum: a methodological and developmental study
TLDR
The corpus callosa of 104 right-handed healthy children and adolescents, ages 4-18, were examined in relation to age and sex and results indicate that the method is reliable and sensitive to developmental changes of the CC.
Fiber composition of the human corpus callosum
TLDR
Across subjects, the overall density of callosal fibers had no significant correlation withcallosal area and an increased callosal area indicated an increased total number of fibers crossing through, and this was only true for small diameter fibers, whose large majority is believed to interconnect association cortex.
Less developed corpus callosum in dyslexic subjects—a structural MRI study
TLDR
A clear shape difference in the posterior midbody of the CC was found between dyslexic and control subjects, which fits with recent other studies that have reported a strong growth factor in this CC region during the late childhood years, coinciding with literacy acquisition.
Altered interhemispheric connectivity in individuals with Tourette's disorder.
TLDR
It is suggested that neural plasticity may contribute to smaller corpus callosum size in persons with Tourette's disorder, which thereby limits neuronal trafficking across the cerebral hemispheres and reduces input to cortical inhibitory interneurons within the prefrontal cortices.
Genetic Contributions to Altered Callosal Morphology in Schizophrenia
TLDR
It is shown that genetic rather than disease-specific or shared environmental influences contribute to altered callosal morphology in schizophrenia, and an upward bowing of the callosum may provide an easily identifiable neuroanatomic marker to screen individuals possessing a biological vulnerability for schizophrenia.
Hand and sex differences in the isthmus and genu of the human corpus callosum. A postmortem morphological study.
The midsagittal area of the corpus callosum was measured in its entirety and in seven subdivisions in a sample of 50 brains consecutively obtained from autopsies of individuals who had
...
1
2
3
...