Topography of dopamine transporter availability in progressive supranuclear palsy: a voxelwise [123I]beta-CIT SPECT analysis.

@article{Seppi2006TopographyOD,
  title={Topography of dopamine transporter availability in progressive supranuclear palsy: a voxelwise [123I]beta-CIT SPECT analysis.},
  author={Klaus Seppi and Christoph Scherfler and E. Donnemiller and Irene Johanna Virgolini and Michael F. H. Schocke and Georg G{\"o}bel and Katherina J. Mair and Sylvia M. Boesch and Christian Brenneis and Gregor Karl Wenning and Werner Poewe},
  journal={Archives of neurology},
  year={2006},
  volume={63 8},
  pages={
          1154-60
        }
}
BACKGROUND Dopaminergic loss can be visualized by means of iodine I 123-labeled 2beta-carbomethoxy-3beta-(4-iodophenyl)tropane ([(123)I]beta-CIT) single-photon emission computed tomography (SPECT) in several neurodegenerative parkinsonian disorders. Most previous SPECT studies have adopted region-of-interest methods for analysis, which are subjective and operator dependent. OBJECTIVE To objectively localize the cerebral dopamine transporter status in the early stages of progressive… CONTINUE READING
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