Topography of callosal atrophy reflects distribution of regional cerebral volume reduction in Alzheimer’s disease

@article{Pantel1999TopographyOC,
  title={Topography of callosal atrophy reflects distribution of regional cerebral volume reduction in Alzheimer’s disease},
  author={Johannes Pantel and Johannes Schr{\"o}der and Marek Jauss and Marco Essig and Michael V. Knopp},
  journal={Psychiatry Research: Neuroimaging},
  year={1999},
  volume={90},
  pages={181-192}
}
It has been suggested that regional corpus callosum atrophy in Alzheimer's disease (AD) may serve as an in vivo index of neuronal loss in the neocortex. In this study total and regional size of the corpus callosum was evaluated with respect to the volumes of the frontal, temporal, and parietal lobes in 38 patients with AD (NINCDS-ADRDA criteria) using quantitative magnetic resonance imaging. Twenty healthy subjects matched for age and gender served as a control group. All quantitative… CONTINUE READING

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