Topography of RNA in the ribosome: location of the 3'-end of 5 S RNA on the central protuberance of the 50 S subunit.


The 5 S RNA is an integral part of the prokaryotic ribosome and plays an important role in polypeptide synthesis. However, the specific function of 5 S RNA and/or associated proteins is unknown” The removal of 5 S RNA from 50 S ribosomal subunits strongly impairs various functional activities of ribosomes [ 1,2]. The o&y exception is the EF-Gdependent GTP… (More)