Topographically specific regeneration of sensory axons in the spinal cord.

@article{Harvey2010TopographicallySR,
  title={Topographically specific regeneration of sensory axons in the spinal cord.},
  author={Pamela A Harvey and Bangjian Gong and Anthony J Rossomando and Eric Frank},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2010},
  volume={107 25},
  pages={11585-90}
}
Artemin, a member of the glial-derived neurotrophic factor family, promotes robust regeneration of sensory axons after dorsal root crush. We report here that several classes of sensory axons regenerate to topographically appropriate regions of the dorsal horn with artemin treatment. Projections of regenerated muscle and cutaneous myelinated sensory afferents are restricted to the correct spinal segments and to appropriate regions within spinal gray matter. Regenerated unmyelinated axons… CONTINUE READING

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