Topographically and chemically modified surfaces for expansion or differentiation of embryonic stem cells

@inproceedings{Markert2011TopographicallyAC,
  title={Topographically and chemically modified surfaces for expansion or differentiation of embryonic stem cells},
  author={Lotte D Markert and Jette Lovmand and Mogens Ryttergaard Duch and Finn Skou Pedersen},
  year={2011}
}
Cells in the body respond to signals emanating from the interaction with neighbouring cells, from the surrounding extracellular matrix, and from soluble signalling molecules. These signals are perceived by the cell as topographical, mechanical, and chemical cues (Martinez et al., 2009). One example of a defined physical topography embedded in the extracellular matrix (ECM) is provided by the collagen structure. Collagen molecules are about 300 nm long and 1.5 nm wide and can form fibrils up to… CONTINUE READING

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