Topographical expression of class IA and class II phosphoinositide 3-kinase enzymes in normal human tissues is consistent with a role in differentiation

@article{Sheikh2003TopographicalEO,
  title={Topographical expression of class IA and class II phosphoinositide 3-kinase enzymes in normal human tissues is consistent with a role in differentiation},
  author={Soha Salama El Sheikh and Jan Domin and Prakitpunthu Tomtitchong and Paul David Abel and Gordon Stamp and E N Lalani},
  journal={BMC Clinical Pathology},
  year={2003},
  volume={3},
  pages={4 - 4}
}
BACKGROUND: Growth factor, cytokine and chemokine-induced activation of PI3K enzymes constitutes the start of a complex signalling cascade, which ultimately mediates cellular activities such as proliferation, differentiation, chemotaxis, survival, trafficking, and glucose homeostasis. The PI3K enzyme family is divided into 3 classes; class I (subdivided into IA and IB), class II (PI3K-C2alpha, PI3K-C2beta and PI3K-C2gamma) and class III PI3K. Expression of these enzymes in human tissue has not… CONTINUE READING

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Immunocytochemical Detection of Phosphatidylinositol 3-kinase Activation by Insulin and Leptin

  • D. Niswender Kevin, Byron Gallis, E. Blevins James, A. Corson Marshall, W. Schwartz Michael, G. Baskin Denis
  • J. Histochem. Cytochem
  • 2003
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