Topographic variation in redifferentiation capacity of chondrocytes in the adult human knee joint.

@article{Stenhamre2008TopographicVI,
  title={Topographic variation in redifferentiation capacity of chondrocytes in the adult human knee joint.},
  author={Hanna Stenhamre and Konrad Slynarski and C Petr{\'e}n and Tommi Tallheden and Anders H Lindahl},
  journal={Osteoarthritis and cartilage},
  year={2008},
  volume={16 11},
  pages={1356-62}
}
OBJECTIVES The aim of this study was to investigate the topographic variation in matrix production and cell density in the adult human knee joint. Additionally, we have examined the redifferentiation potential of chondrocytes expanded in vitro from the different locations. METHOD Full thickness cartilage-bone biopsies were harvested from seven separate anatomical locations of healthy knee joints from deceased adult human donors. Chondrocytes were isolated, expanded in vitro and… CONTINUE READING
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