Topographic reorganization of somatosensory cortical areas 3b and 1 in adult monkeys following restricted deafferentation

@article{Merzenich1983TopographicRO,
  title={Topographic reorganization of somatosensory cortical areas 3b and 1 in adult monkeys following restricted deafferentation},
  author={M. M. Merzenich and Jon H. Kaas and John Wall and Randall Nelson and Mriganka Sur and D. J. Felleman},
  journal={Neuroscience},
  year={1983},
  volume={8},
  pages={33-55}
}

Functional reorganization of primary somatosensory cortex in adult owl monkeys after behaviorally controlled tactile stimulation.

TLDR
These experiments demonstrate that functional cortical remodeling of the S1 koniocortical field, area 3b, results from behavioral manipulations in normal adult owl monkeys.

A Histologically Visible Representation of the Fingers and Palm in Primate Area 3 b and its Immutability Following Long-term

TLDR
It is concluded that the anatomical isomorph for the body surface representation in area 3b is a reliable reflection of normal cortical organization and may be a common feature of the primate area 2b, and can provide a reference in studies of somatotopic reorganization.

Pattern of peripheral deafferentation predicts reorganizational limits in adult primate somatosensory cortex.

TLDR
The reorganization that can occur in somatosensory cortex following peripheral sensory loss is constrained by the precise content of the stimulus deprivation; that is, there is a limit to the set of new receptive fields cortical neurons can acquire.

Functional reorganization in somatosensory cortical areas 3b and 1 of adult monkeys after median nerve repair: possible relationships to sensory recovery in humans

TLDR
The results suggest that nerve regeneration reestablishes the cortical capacity to process tactile information from reinnervated skin via a prolonged reorganizational process that appears dependent on peripheral and central factors.

Reorganization of Somatosensory Cortical Areas 3b and 1 after Unilateral Section of Dorsal Columns of the Spinal Cord in Squirrel Monkeys

TLDR
The results indicate that extensive reactivations of the hand representations in cortical areas 3b and 1 occur contralateral to the spinal cord lesion, even when <1% of labeled dorsal column terminations in the cuneate nucleus remained.

A histologically visible representation of the fingers and palm in primate area 3b and its immutability following long-term deafferentations.

TLDR
It is concluded that the anatomical isomorph for the body surface representation in area 3B is a reliable reflection of normal cortical organization and may be a common feature of the primate area 3b.

Variability in hand surface representations in areas 3b and 1 in adult owl and squirrel monkeys

TLDR
Detailed microelectrode maps of the hand representation were derived in cortical areas 3b and 1 from a series of normal adult owl and squirrel monkeys, and all maps were internally topographic.

Time-dependent changes in the functional organization of somatosensory cerebral cortex following digit amputation in adult raccoons.

TLDR
The combined results of these experiments indicate that within 36 weeks following removal of a digit in raccoons, the deprived SmI cortical sector undergoes a dynamic sequence of changes in functional organization.

Large-Scale Reorganization in the Somatosensory Cortex and Thalamus after Sensory Loss in Macaque Monkeys

TLDR
A comparison of the extents of deafferentation across the monkeys shows that even if the dorsal column lesion is partial, preserving most of the hand representation, it is sufficient to induce an expansion of the face representation.
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References

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Magnification, receptive-field area, and "hypercolumn" size in areas 3b and 1 of somatosensory cortex in owl monkeys.

TLDR
The area of cortex presumed to receive all fibers from any given receptive field was obtained and found to be independent of the body surface represented and may be akin to the “hypercolumn” proposed for primary visual cortex.

Representations of the body surface in postcentral parietal cortex of Macaca fascicularis

TLDR
The somatotopic organization of the postcentral parietal cortex of the Old World monkey, Macaca fascicularis, was determined with multi‐unit microelectrode recordings and it is suggested that the representation in Area 3b is homologous to “SmI” (or “SI”) in non‐primates.

Double representation of the body surface within cytoarchitectonic area 3b and 1 in “SI” in the owl monkey (aotus trivirgatus)

Microelectrode multiunit mapping studies of parietal cortex in owl monkeys indicate that the classical “primary” somatosensory region (or “SI”) including the separate architectonic fields 3a, 3b, 1,

Properties of synaptic linkage from long ranging afferents onto dorsal horn neurones in normal and deafferented cats.

TLDR
Chronic deafferentation of a segment increased the number of cells responding to afferents arriving over distal dorsal roots and increased the speed and power of the responses.