Topographic mapping between basal forebrain cholinergic neurons and the medial prefrontal cortex in mice.

@article{Bloem2014TopographicMB,
  title={Topographic mapping between basal forebrain cholinergic neurons and the medial prefrontal cortex in mice.},
  author={Bernard Bloem and Luc Schoppink and Diana C Rotaru and Amu Faiz and Patrick Hendriks and Huibert D. Mansvelder and Wilma D J van de Berg and Floris G Wouterlood},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2014},
  volume={34 49},
  pages={
          16234-46
        }
}
The basal forebrain cholinergic innervation of the medial prefrontal cortex (mPFC) is crucial for cognitive performance. However, little is known about the organization of connectivity between the basal forebrain and the mPFC in the mouse. Using focal virus injections inducing Cre-dependent enhanced yellow fluorescent protein expression in ChAT-IRES-Cre mice, we tested the hypothesis that there is a topographic mapping between the basal forebrain cholinergic neurons and their axonal projections… CONTINUE READING

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