Topiramate in treatment of patients with chronic low back pain: a randomized, double-blind, placebo-controlled study.

@article{Muehlbacher2006TopiramateIT,
  title={Topiramate in treatment of patients with chronic low back pain: a randomized, double-blind, placebo-controlled study.},
  author={Moritz Muehlbacher and Marius K. Nickel and Christian Kettler and Karin Tritt and Claas Lahmann and Peter K Leiberich and Cerstin Nickel and Jakub Krawczyk and Ferdinand O Mitterlehner and Wolfhardt K Rother and Thomas H. Loew and Patrick Kaplan},
  journal={The Clinical journal of pain},
  year={2006},
  volume={22 6},
  pages={526-31}
}
OBJECTIVE Chronic low back pain (CLBP) is a widespread ailment. The aim of this study was to assess the efficacy of topiramate in the treatment of CLBP and the changes in anger status and processing, body weight, subjective pain-related disability and health-related quality of life during the course of treatment. METHODS We conducted a 10-week, randomized, double-blind, placebo-controlled study of topiramate in 96 (36 women) patients with CLBP. The subjects were randomly assigned to… CONTINUE READING

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