Topiramate in the prophylaxis of pediatric migraine: a double-blind placebo-controlled trial.

@article{Lakshmi2007TopiramateIT,
  title={Topiramate in the prophylaxis of pediatric migraine: a double-blind placebo-controlled trial.},
  author={C. Sree Lakshmi and Pratibha D. Singhi and Prahbhjot Malhi and Munni Ray},
  journal={Journal of child neurology},
  year={2007},
  volume={22 7},
  pages={829-35}
}
Several large, randomized controlled trials have demonstrated the efficacy of topiramate in migraine prophylaxis in adults. However, there are limited data about the use of topiramate in migraine prophylaxis in children. We conducted this single-center, double-blind, placebo-controlled trial to evaluate the efficacy and safety of topiramate in the prophylaxis of migraine in children. A total of 44 children with migraine were randomized using random number tables to receive topiramate (n = 22… CONTINUE READING

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