Topiramate for the treatment of binge eating disorder associated with obesity: a placebo-controlled study.

@article{McElroy2007TopiramateFT,
  title={Topiramate for the treatment of binge eating disorder associated with obesity: a placebo-controlled study.},
  author={Susan L McElroy and James I. Hudson and Julie A Capece and Karen Beyers and Alan C. Fisher and Norman R Rosenthal},
  journal={Biological psychiatry},
  year={2007},
  volume={61 9},
  pages={1039-48}
}
BACKGROUND In a single-center, placebo-controlled study, topiramate reduced binge eating and weight in patients with binge eating disorder (BED) and obesity. The current investigation evaluated the safety and efficacy of topiramate in a multicenter, placebo-controlled trial. METHODS Eligible patients between 18 and 65 years with >or= 3 binge eating days/week and a body mass index (BMI) between 30 and 50 kg/m2 were randomized. RESULTS A total of 407 patients enrolled; 13 failed to meet… CONTINUE READING
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