Topiramate as add-on drug in children, adolescents and young adults with Lennox-Gastaut syndrome: an Italian multicentric study

@article{Coppola2002TopiramateAA,
  title={Topiramate as add-on drug in children, adolescents and young adults with Lennox-Gastaut syndrome: an Italian multicentric study},
  author={G. Coppola and G. Caliendo and P. Veggiotti and A. Romeo and A. Pascotto},
  journal={Epilepsy Research},
  year={2002},
  volume={51},
  pages={147-153}
}
  • G. Coppola, G. Caliendo, +2 authors A. Pascotto
  • Published 2002
  • Medicine
  • Epilepsy Research
  • The purpose of the study was to evaluate the efficacy and safety of topiramate (TPM) as adjunctive therapy in children, adolescents and young adults with Lennox-Gastaut syndrome (LGS). We performed a prospective open label add-on study in 45 patients (age 4-34 years, mean 15.9 years) with LGS and refractory seizures. TPM was added to one or two other baseline drugs and the efficacy was rated according to seizure type and frequency. TPM was initiated at the daily dose of 0.5-1 mg/kg, followed by… CONTINUE READING
    42 Citations
    Topiramate in Children With West Syndrome: A Retrospective Multicenter Evaluation of 100 Patients
    • 36
    Efficacy and Tolerability of Topiramate in Children Younger Than 2 Years Old
    • 23
    Topiramate in long-term treatment of epilepsy in the intellectually disabled.
    • 20

    References

    SHOWING 1-10 OF 30 REFERENCES
    A pilot study of topiramate in children with Lennox-Gastaut syndrome.
    • 15
    • PDF
    Clinical experiences with topiramate in children with intractable epilepsy.
    • P. Uldall, J. Buchholt
    • Medicine
    • European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
    • 1999
    • 39
    Topiramate in intractable childhood onset epilepsy--a cautionary note.
    • 32
    • PDF
    A Risk-Benefit Assessment of Therapies for Lennox-Gastaut Syndrome
    • 77
    Topiramate for drug-resistant epilepsies.
    • 26