Topically administered immunoglobulin reduces pulmonary respiratory syncytial virus shedding in owl monkeys.

@article{Hemming1988TopicallyAI,
  title={Topically administered immunoglobulin reduces pulmonary respiratory syncytial virus shedding in owl monkeys.},
  author={Val G. Hemming and Gregory A. Prince and William T London and Paul A. Baron and Roger Brown and Robert M. Chanock},
  journal={Antimicrobial agents and chemotherapy},
  year={1988},
  volume={32 8},
  pages={1269-70}
}
A human intravenous immunoglobulin preparation containing neutralizing antibodies to respiratory syncytial virus (RSV) was utilized for intratracheal and topical treatment of laboratory-induced RSV infections in owl monkeys (Aotus trivirgatus). Topically administered antibodies induced significant reductions in RSV shedding in the lower respiratory tract.