Topically Administered Ketamine Reduces Capsaicin-Evoked Mechanical Hyperalgesia

@article{Pyhi2006TopicallyAK,
  title={Topically Administered Ketamine Reduces Capsaicin-Evoked Mechanical Hyperalgesia},
  author={R. P{\"o}yhi{\"a} and A. Vainio},
  journal={The Clinical Journal of Pain},
  year={2006},
  volume={22},
  pages={32-36}
}
  • R. Pöyhiä, A. Vainio
  • Published 2006
  • Medicine
  • The Clinical Journal of Pain
    • Background:The n-methyl-d-aspartate receptor antagonists such as ketamine relieve chronic pain but their oral and parenteral use is limited by the adverse effects. Experimental studies indicate that the peripheral n-methyl-d-aspartate receptors are involved in nociception. Recent clinical findings suggest that ketamine gel alleviates neuropathic pain, but no placebo-controlled randomized studies are available on the neurosensory effects of ketamine gel in experimental neurogenic pain… CONTINUE READING
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    Paper Mentions

    Observational Clinical Trial
    Blood Levels of Ketamine in Patients Using Topical Application of 10% Ketamine Gel for Neuropathic Pain
    The purpose of this research study is to measure how much, if any, ketamine is absorbed into the blood stream after ketamine gel is applied to the skin. The investigators expect that the… Expand
    ConditionsNeuropathic Pain.
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    June 2011 - December 2011
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