Topical zoledronic acid decreases micromotion induced bone resorption in a sheep arthroplasty model

@inproceedings{Jakobsen2017TopicalZA,
  title={Topical zoledronic acid decreases micromotion induced bone resorption in a sheep arthroplasty model},
  author={Thomas Jakobsen and S\oren V Kold and Juan Manuel Shiguetomi-Medina and J\orgen Baas and Kjeld Soballe and Ole Rahbek},
  booktitle={BMC musculoskeletal disorders},
  year={2017}
}
BACKGROUND Initial micromotion of a total hip replacement is associated with aseptic loosening. The use of bisphosphonates could be one way to reduce peri-implant bone resorption induced by micromotion. Bisphosphonates compounds are inhibitors of bone resorption. The aim of this study was to investigate whether local treatment with bisphosphonate would… CONTINUE READING