Topical use of coenzyme Q10-loaded liposomes coated with trimethyl chitosan: tolerance, precorneal retention and anti-cataract effect.

@article{Zhang2009TopicalUO,
  title={Topical use of coenzyme Q10-loaded liposomes coated with trimethyl chitosan: tolerance, precorneal retention and anti-cataract effect.},
  author={Jing Zhang and Siling Wang},
  journal={International journal of pharmaceutics},
  year={2009},
  volume={372 1-2},
  pages={66-75}
}
The effects of the molecular weight (MW) and concentration of trimethyl chitosan (TMC) on the characteristics of Coenzyme Q10-loaded liposomes coated with trimethyl chitosan were investigated while the efficacy of the antioxidant Coenzyme Q10 in delaying selenite-induced cataract was assessed. The existence of a thick polymer layer on the surface of the liposomes nanoparticle system was affirmed by transmission electron microscopy (TEM) analysis and the changes in particle size distribution and… CONTINUE READING

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