Topical treatment with nerve growth factor for neurotrophic keratitis.

  title={Topical treatment with nerve growth factor for neurotrophic keratitis.},
  author={Stefano Bonini and Alessandro Lambiase and Paolo Rama and G Caprioglio and Luigi Aloe},
  volume={107 7},
  pages={1347-51; discussion 1351-2}
OBJECTIVE To evaluate the efficacy of nerve growth factor (NGF) in patients with neurotrophic keratitis. DESIGN Prospective, noncomparative, interventional case series. PARTICIPANTS Forty-five eyes of 43 consecutive patients with moderate (stage 2, n = 17) to severe (stage 3, n = 28) neurotrophic keratitis unresponsive to other nonsurgical therapies. METHODS After a 10-day washout with preservative-free artificial tears, 45 eyes with neurotrophic keratitis received murine NGF (200 microg… CONTINUE READING
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