Topical treatment of cutaneous metastases of malignant melanoma using combined imiquimod and 5-fluorouracil

@article{Florin2011TopicalTO,
  title={Topical treatment of cutaneous metastases of malignant melanoma using combined imiquimod and 5-fluorouracil},
  author={Val{\'e}rie Florin and Eve Desmedt and Sophie Vercambre-Darras and Laurent Mortier},
  journal={Investigational New Drugs},
  year={2011},
  volume={30},
  pages={1641-1645}
}
Background Despite multiple available options, the treatment of cutaneous melanoma metastases is often unsuccessful. Based on the hypothesis that imiquimod and 5-fluorouracil have synergistic antitumor properties, we used this topical combination to treat several patients. Aim Our objective was to investigate the treatment combination in a small cohort of patients with surgically non-resectable melanoma metastases. Methods The lesions of 5 patients with multiple cutaneous metastases were… CONTINUE READING
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