Topical pimecrolimus for skin disease other than atopic dermatitis

@article{Wollina2006TopicalPF,
  title={Topical pimecrolimus for skin disease other than atopic dermatitis},
  author={Uwe Wollina and Gesina Hansel and A Koch and Mohamed Badawy Abdel-Naser},
  journal={Expert Opinion on Pharmacotherapy},
  year={2006},
  volume={7},
  pages={1967 - 1975}
}
Pimecrolimus is an ascomycin macrolactam. It is a specific calcineurin inhibitor that allows topical application. The highly lipophilic nature of this compound reduces the risk of systemic absorption through normal and inflammed skin. Pimecrolimus shows activity not only against T-cell activation, but also against mast cells and pruritus. Pimecrolimus 1% cream is approved for atopic dermatitis, and also has a great potential in other inflammatory skin diseases. Clinical trials have been… Expand
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Available data indicates that pimecrolimus, in both the cream and oral formulations, may represent a new option for the treatment of inflammatory skin diseases. Expand
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It is suggested that pimecrolimus 1% cream could be an efficacious and safe treatment option for cutaneous lupus erythematosus. Expand
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