Topical growth factors and wound contraction in the rat: Part I. Literature review and definition of the rat model.

@article{Richey1989TopicalGF,
  title={Topical growth factors and wound contraction in the rat: Part I. Literature review and definition of the rat model.},
  author={K J Richey and Loren H. Engrav and Edward G Pavlin and Merritt J. Murray and Jourdan R. Gottlieb and Marcus D. Walkinshaw},
  journal={Annals of plastic surgery},
  year={1989},
  volume={23 2},
  pages={159-65}
}
The isolation and production of growth factors and the observation that a platelet extract will promote wound healing in chronic wounds has led to an interest in the study of growth factors and wound healing. We wished to study the effect of platelet-derived growth factor on wound contraction. However, because studies of growth factors and wound contraction are quite recent, we could find only two models described in the literature and neither seemed ideal. Both used small wounds, which are… CONTINUE READING

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