Topical formulations of novel angiostatic steroids inhibit rabbit corneal neovascularization.

@article{Benezra1997TopicalFO,
  title={Topical formulations of novel angiostatic steroids inhibit rabbit corneal neovascularization.},
  author={David Benezra and Brenda W. Griffin and Genia Maftzir and Najam A Sharif and Abbot F. Clark},
  journal={Investigative ophthalmology & visual science},
  year={1997},
  volume={38 10},
  pages={1954-62}
}
PURPOSE To evaluate the antiangiogenic potential of topical ophthalmic formulations of the novel angiostatic steroids AL-3789 and AL-4940, using a rabbit model of corneal neovascularization. METHODS Neovascularization was induced in the rabbit cornea by surgical implantation of a standard ethylene vinyl acetate copolymer (Elvax-40) pellet containing 1 microg lipopolysaccharide. Coded formulations of the control vehicle or the following test agents were administered in prevention and… CONTINUE READING
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