Topical chemoprevention of oral cancer with tretinoin "biofilm".

  title={Topical chemoprevention of oral cancer with tretinoin "biofilm".},
  author={Zhi Wang and Raju Polavaram and Cesar F Fuentes and Stanley M Shapshay},
  journal={Archives of otolaryngology--head & neck surgery},
  volume={129 8},
BACKGROUND Oral cancer is a common malignancy. Chemoprevention is a promising treatment strategy but it produces systemic toxic effects. Topical application of chemopreventive agents is an attractive alternative that reduces toxic effects. This study is based on the hypothesis that topical application of mucosal adhesive film (MAF), as a means to deliver… CONTINUE READING