Topical application of epidermal growth factor accelerates wound healing by myofibroblast proliferation and collagen synthesis in rat

@inproceedings{Kwon2006TopicalAO,
  title={Topical application of epidermal growth factor accelerates wound healing by myofibroblast proliferation and collagen synthesis in rat},
  author={Young-Bae Kwon and Hyun-Woo Kim and D H Roh and S Y Yoon and Rong-Min Baek and Jeum-Yong Kim and Haeyong Kweon and Kwang-gill Lee and Young-hwan Park and Jang-Hern Lee},
  booktitle={Journal of veterinary science},
  year={2006}
}
Recombinant human epidermal growth factor (rhEGF) stimulates the proliferation and migration of epithelial cells in human cell culture systems and animal models of partial-thickness skin wounds. This study investigated the effect of a topical rhEGF ointment on the rate of wound healing and skin re-epithelialization in a rat full thickness wound model, and verified whether or not the rhEGF treatment affected both myofibroblast proliferation and collagen synthesis in the dermis. When rhEGF (10… CONTINUE READING

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