Topical application of calcium channel blockers to reduce the progression of experimentally induced myringosclerosis and tympanosclerosis.

@article{Seluk2008TopicalAO,
  title={Topical application of calcium channel blockers to reduce the progression of experimentally induced myringosclerosis and tympanosclerosis.},
  author={A Birkan Selçuk and Ozgur Akdogan and I Turkay Ozcan and Seren Gulsen Giray and Huseyin Dere and Candan Ozoğul},
  journal={The Laryngoscope},
  year={2008},
  volume={118 4},
  pages={697-705}
}
OBJECTIVES This study aimed to evaluate the ability of topically applied calcium channel blockers (diltiazem) to reduce the progression of experimentally induced myringosclerosis and tympanosclerosis. STUDY DESIGN Animal model. Experimental prospective study. METHODS The study included 25 adult albino guinea pigs that were bilaterally myringotomized and inoculated with a suspension of Streptococcus pneumonia type 3. The right ears were treated with topical application of diltiazem, and the… CONTINUE READING

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