Topical application of bleaching phenols; in-vivo studies and mechanism of action relevant to melanoma treatment.


Skin depigmentation represents a well-established treatment for extensive vitiligo and may likewise be suited to prevent tumor recurrences and as a prophylactic treatment of familial melanoma, as common bleaching agents are cytotoxic to melanocytes. Effective melanoma prevention requires a bleaching agent-induced loss of exposed melanocytes supported by an… (More)
DOI: 10.1097/CMR.0b013e328343f542

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