Topical application of Calendula officinalis (L.): Formulation and evaluation of hydrophilic cream with antioxidant activity

@article{Bernatonien2011TopicalAO,
  title={Topical application of Calendula officinalis (L.): Formulation and evaluation of hydrophilic cream with antioxidant activity},
  author={J. Bernatonienė and R. Masteikov{\'a} and J. Davalgiene and R. Pe{\vc}iūra and Romualda Gaurylienė and R. Bernatonienė and D. Majiene and Robertas La{\vz}auskas and G. Civinskienė and S. Vel{\vz}ienė and J. Musel{\'i}k and Z. Chalupov{\'a}},
  journal={Journal of Medicinal Plants Research},
  year={2011},
  volume={5},
  pages={868-877}
}
  • J. Bernatonienė, R. Masteiková, +9 authors Z. Chalupová
  • Published 2011
  • Chemistry
  • Journal of Medicinal Plants Research
  • The aim of the study was the formulation of suitable medicinal form for the topical application of Calendula officinalis L. Dry Calendula extract was used as an active compound. This extract was proved to be an effective scavenger of H2O2 radicals in in vitrostudies with the mitochondria of rat cardiac muscles. Several compositions of the cream base were evaluated and the hydrophilic cream containing complex emulsifier was chosen as the delivery system. Subsequently, Calendula extract was… CONTINUE READING
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