Topical anti-inflammatory potential of Physalin E from Physalis angulata on experimental dermatitis in mice.

Abstract

The anti-inflammatory effect of physalin E, a seco-steroid isolated from Physalis angulata L. was evaluated on acute and chronic models of dermatitis induced by 12-O-tetradecanoyl-phorbol-13-acetate (TPA) and oxazolone, respectively, in mouse ear. The changes in ear edema/thickness, production of pro-inflammatory cytokines (TNF-alpha and IFN-gamma… (More)
DOI: 10.1016/j.phymed.2010.01.006

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