Topical administration of a multi-targeted kinase inhibitor suppresses choroidal neovascularization and retinal edema.


Age-related macular degeneration, diabetic retinopathy, and retinal vein occlusions are complicated by neovascularization and macular edema. Multi-targeted kinase inhibitors that inhibit select growth factor receptor tyrosine kinases and/or components of their down-stream signaling cascades (such as Src kinases) are rationale treatment strategies for these… (More)
DOI: 10.1002/jcp.21426


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