Topical acne treatments in Europe and the issue of antimicrobial resistance

@article{Leccia2015TopicalAT,
  title={Topical acne treatments in Europe and the issue of antimicrobial resistance},
  author={Marie Th{\'e}r{\`e}se Leccia and Nicole Auffret and Florence Poli and Jean Paul Claudel and St{\'e}phane Corvec and Brigitte Dr{\'e}no},
  journal={Journal of the European Academy of Dermatology and Venereology},
  year={2015},
  volume={29}
}
  • M. LecciaN. Auffret B. Dréno
  • Published 1 August 2015
  • Biology, Medicine
  • Journal of the European Academy of Dermatology and Venereology
Acne vulgaris (acne) is a chronic inflammatory disease of the sebaceous gland, characterized by follicular hyperkeratinization, excessive colonization by Propionibacterium acnes (P. acnes) as well as immune reactions and inflammation. Despite an armamentarium of topical treatments available including benzoyl peroxide, retinoids and azelaic acid, topical antibiotics in monotherapies, especially erythromycin and clindamycin, are still used in Europe to treat acne. This intensive use led to… 
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