Topical Zinc in the Treatment of Mice Infected Intravaginally with Herpes Genitalis Virus

@article{Tennican1980TopicalZI,
  title={Topical Zinc in the Treatment of Mice Infected Intravaginally with Herpes Genitalis Virus},
  author={P. Tennican and G. Carl and J. Frey and C. Thies and M. Chvapil},
  journal={Proceedings of the Society for Experimental Biology and Medicine},
  year={1980},
  volume={164},
  pages={593 - 597}
}
Abstract The course of the disease, HSV-2, inoculated intravaginally in immature mice was ascertained by studying the incidence of vaginitis, encephalitis, and mortality rate. The therapeutic efficacy of various zinc containing medications administered topically 4 hr after infection was studied. It was found that intravaginally applied zinc medicated collagen sponge containing 50 μg zinc sulfate (7H2O) in acetate buffer, pH 5.5, significantly improved the course of disease and was significantly… Expand
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