Topical Tetrodotoxin Attenuates Photophobia Induced by Corneal Injury in the Rat.

Abstract

Corneal injury can produce photophobia, an aversive sensitivity to light. Using topical application of lidocaine, a local anesthetic, and tetrodotoxin (TTX), a selective voltage-sensitive sodium channel blocker, we assessed whether enhanced aversiveness to light induced by corneal injury in rats was caused by enhanced activity in corneal afferents. Eye… (More)
DOI: 10.1016/j.jpain.2015.06.002

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@article{Green2015TopicalTA, title={Topical Tetrodotoxin Attenuates Photophobia Induced by Corneal Injury in the Rat.}, author={Paul Green and Pedro Mejı́a Alvarez and Jon D Levine}, journal={The journal of pain : official journal of the American Pain Society}, year={2015}, volume={16 9}, pages={881-6} }