Topical S-nitrosoglutathione-releasing hydrogel improves healing of rat ischaemic wounds.

@article{Georgii2011TopicalSH,
  title={Topical S-nitrosoglutathione-releasing hydrogel improves healing of rat ischaemic wounds.},
  author={Jana{\'i}na L Georgii and Tha{\'i}s Porto Amadeu and Amedea Barozzi Seabra and Marcelo Ganzarolli de Oliveira and Andr{\'e}a Monte-Alto-Costa},
  journal={Journal of tissue engineering and regenerative medicine},
  year={2011},
  volume={5 8},
  pages={612-9}
}
Topical application of the nitric oxide (NO) donor S-nitrosoglutathione (GSNO) is known to exert beneficial effects on wound healing. The aim of this study was to evaluate, for the first time, the effect of topical application of GSNO on the healing of ischaemic wounds. Wistar rats were submitted to two parallels incisions on their backs; the skin was separated from the underlying tissue, the incisions were sutured and an excisional wound was made between the parallel incisions to create an… CONTINUE READING
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