Topical Retinoids: Therapeutic Mechanisms in the Treatment of Photodamaged Skin
@article{Riahi2016TopicalRT, title={Topical Retinoids: Therapeutic Mechanisms in the Treatment of Photodamaged Skin}, author={Ryan R. Riahi and Amelia E Bush and Philip R. Cohen}, journal={American Journal of Clinical Dermatology}, year={2016}, volume={17}, pages={265-276} }
Retinoids are a group of substances comprising vitamin A and its natural and synthetic derivatives. Retinoids were first used in dermatology in 1943 by Straumfjord for acne vulgaris. Since that time, retinoids have been utilized in the management and treatment of various skin conditions, including photoaging. Photodamage of the skin occurs as a consequence of cumulative exposure to solar ultraviolet radiation (UVR) and is characterized by deep wrinkles, easy bruising, inelasticity, mottled… Expand
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References
SHOWING 1-10 OF 75 REFERENCES
Topical retinoids in the management of photodamaged skin: from theory to evidence‐based practical approach
- Medicine
- The British journal of dermatology
- 2010
- 62
- Highly Influential
The Mechanism of Action of Topical Retinoids for the Treatment of Nonmalignant Photodamage , Part 1
- 2010
- 1
- Highly Influential
- PDF
The role of retinoids in the prevention and repair of aged and photoaged skin
- Medicine
- Clinical and experimental dermatology
- 2001
- 47
- Highly Influential
Photoaging: pathogenesis, prevention, and treatment.
- Medicine
- Clinics in geriatric medicine
- 2001
- 104
- Highly Influential
Treatment of capecitabine-induced hand-foot syndrome using a topical retinoid: A case report
- Medicine
- Oncology letters
- 2014
- 8
- Highly Influential
- PDF
One-year topical stabilized retinol treatment improves photodamaged skin in a double-blind, vehicle-controlled trial.
- Medicine
- Journal of drugs in dermatology : JDD
- 2015
- 11
Open-label pilot study of alitretinoin gel 0.1% in the treatment of photoaging.
- Medicine
- Cutis
- 2005
- 25
- PDF
Topical Retinoids in Skin Ageing: A Focused Update with Reference to Sun-Induced Epidermal Vitamin A Deficiency
- Biology, Medicine
- Dermatology
- 2014
- 23
- Highly Influential
The Tolerability and Efficacy of a Three-product Anti-aging Treatment Regimen in Subjects with Moderate-to-severe Photodamage.
- Medicine
- The Journal of clinical and aesthetic dermatology
- 2015
- 3