Topical Retinoids: Therapeutic Mechanisms in the Treatment of Photodamaged Skin

@article{Riahi2016TopicalRT,
  title={Topical Retinoids: Therapeutic Mechanisms in the Treatment of Photodamaged Skin},
  author={Ryan R. Riahi and Amelia E Bush and Philip R. Cohen},
  journal={American Journal of Clinical Dermatology},
  year={2016},
  volume={17},
  pages={265-276}
}
Retinoids are a group of substances comprising vitamin A and its natural and synthetic derivatives. Retinoids were first used in dermatology in 1943 by Straumfjord for acne vulgaris. Since that time, retinoids have been utilized in the management and treatment of various skin conditions, including photoaging. Photodamage of the skin occurs as a consequence of cumulative exposure to solar ultraviolet radiation (UVR) and is characterized by deep wrinkles, easy bruising, inelasticity, mottled… 

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