Topical Ketoprofen Patch

@article{Mazires2005TopicalKP,
  title={Topical Ketoprofen Patch},
  author={Bernard Mazi{\`e}res},
  journal={Drugs in R \& D},
  year={2005},
  volume={6},
  pages={337-344}
}
Although oral nonsteroidal anti-inflammatory drugs (NSAIDs) are effective in the treatment of a variety of acute and chronic pain conditions, their use may be associated with serious systemic adverse effects, particularly gastrointestinal disorders. In order to minimise the incidence of systemic events related to such agents, topical NSAIDs have been developed. Topical NSAIDs, applied as gels, creams or sprays, penetrate the skin, subcutaneous fatty tissue and muscle in amounts that are… Expand
Topical Nonsteroidal Anti-Inflammatory Drugs: The Importance of Drug, Delivery, and Therapeutic Outcome
  • R. Barkin
  • Medicine
  • American journal of therapeutics
  • 2015
TLDR
It is important to recognize that pharmacokinetic absorption from topical formulations can vary markedly, even between different formulations of the same drug, depending on the agent, the underlying disorder, and the site of application, and it is essential to consider the patient, the drug, andThe drug delivery mechanism when selecting a topical NSAID preparation. Expand
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The pain branch of the Chinese Medical Association, after meeting and discussing with experts and based on clinical evidence, developed a consensus for promoting and regulating standard use of transdermal patches containing analgesic drugs. Expand
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