Topical Formulations of Serratiopeptidase: Development and Pharmacodynamic Evaluation

@inproceedings{Nirale2010TopicalFO,
  title={Topical Formulations of Serratiopeptidase: Development and Pharmacodynamic Evaluation},
  author={N. M. Nirale and Mala D. Menon},
  booktitle={Indian journal of pharmaceutical sciences},
  year={2010}
}
Serratiopeptidase, an enzyme derived from Serratia marcescences strain E-15 (ATCC 21074), present in the gut wall of the silk worm possesses anti-inflammatory properties, and can prove to be a suitable alternative to commonly used non steroidal antiinflammatory agents. Being sensitive to gastric degradation, serratiopeptidase is conventionally given orally in the form of enteric coated tablet formulations. Topical formulations of serratiopeptidase would be useful to treat local inflammations… CONTINUE READING

Citations

Publications citing this paper.

References

Publications referenced by this paper.
SHOWING 1-10 OF 19 REFERENCES

Composition for topical enzymatic debridement

  • MW Trumbore, RV Rariy, M Hirsh, J Hirsh, JA. Saunders
  • Collegium Pharmaceuticals,
  • 2005
VIEW 1 EXCERPT

Cubic liquid crystalline glyceryl monooleate matrices for oral delivery of enzyme.

VIEW 1 EXCERPT

Temperature responsive in situ mucoadhesive gel for controlled nasal delivery of serratiopeptidase

  • R Jain, VB Patravale
  • CRS 32nd annual meeting and exposition,
  • 2005
VIEW 1 EXCERPT

Analgesic, anti-infl ammatory and anti-pyretic activity in drug and discovery and evaluation, pharmacological assays, 2nd ed

  • GH Vogel
  • 2002
VIEW 1 EXCERPT

Antiarthritic and immunomodulatory activity in Drug and discovery and evaluation, pharmacological assays

  • GH Vogel
  • 2nd ed. Berlin: Springer-Verlag;
  • 2002
VIEW 2 EXCERPTS

Crystal structure of serratia protease: A zinc dependant protinase from serratia sp. E-15, containing a β-sheet coil motif of 2.0 Ao resolution

  • H Kensaku, H Yasuo, +3 authors K. Yukiteru
  • J Biochem 1996;119:844-51
  • 1996
VIEW 1 EXCERPT

Influence of water-miscible aprotic solvents on α-chymotrypsin stability

  • L Pedro, D Teresa de, LI. José
  • Biotechnol Prog
  • 1996
VIEW 1 EXCERPT