Topical Formulations Containing Pimenta pseudocaryophyllus Extract: In Vitro Antioxidant Activity and In Vivo Efficacy Against UV-B-Induced Oxidative Stress

@article{Campanini2013TopicalFC,
  title={Topical Formulations Containing Pimenta pseudocaryophyllus Extract: In Vitro Antioxidant Activity and In Vivo Efficacy Against UV-B-Induced Oxidative Stress},
  author={Marcela Zambrim Campanini and Dayana Lacerda Cust{\'o}dio and Ana Maria Ivan and Sarah Moherdaui Martins and Maria J. R. Paranzini and Renata M. Martinez and Waldiceu A. Jr. Verri and F. D. Vicentini and Nilton Syogo Arakawa and Terezinha J. Faria and Marcela M. Baracat and R{\'u}bia Casagrande and Sandra Regina Georgetti},
  journal={AAPS PharmSciTech},
  year={2013},
  volume={15},
  pages={86-95}
}
Pimenta pseudocaryophyllus is a Brazilian native plant that presents high concentrations of flavonoids and other polyphenolic compounds. Herein, we evaluated: (1) the chemical properties of P. pseudocaryophyllus ethanolic extract (PPE), (2) the in vitro antioxidant activity (AA) of PPE and of two different topical formulations (F1 and F2) containing PPE, (3) physico-chemical and functional stability, (4) in vitro release of PPE, and (5) in vivo capacity of formulations to prevent UV-B… CONTINUE READING
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