Tooth pulp inflammation increases brain-derived neurotrophic factor expression in rodent trigeminal ganglion neurons

@article{Tarsa2010ToothPI,
  title={Tooth pulp inflammation increases brain-derived neurotrophic factor expression in rodent trigeminal ganglion neurons},
  author={L. Tarsa and Ewa Bałkowiec-Iskra and Frantisek Kratochvil and Vernon K. Jenkins and Agnieszka Balkowiec},
  journal={Neuroscience},
  year={2010},
  volume={167},
  pages={1205-1215}
}
Nociceptive pathways with first-order neurons located in the trigeminal ganglion (TG) provide sensory innervation to the head, and are responsible for a number of common chronic pain conditions, including migraines, temporomandibular disorders and trigeminal neuralgias. Many of those conditions are associated with inflammation. Yet, the mechanisms of chronic inflammatory pain remain poorly understood. Our previous studies show that the neurotrophin brain-derived neurotrophic factor (BDNF) is… CONTINUE READING
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