Too Little Exercise and Too Much Sitting: Inactivity Physiology and the Need for New Recommendations on Sedentary Behavior.

@article{Hamilton2008TooLE,
  title={Too Little Exercise and Too Much Sitting: Inactivity Physiology and the Need for New Recommendations on Sedentary Behavior.},
  author={Marc T Hamilton and Genevieve N Healy and David W Dunstan and Theodore W. Zderic and Neville Owen},
  journal={Current cardiovascular risk reports},
  year={2008},
  volume={2 4},
  pages={292-298}
}
Moderate- to vigorous-intensity physical activity has an established preventive role in cardiovascular disease, type 2 diabetes, obesity, and some cancers. However, recent epidemiologic evidence suggests that sitting time has deleterious cardiovascular and metabolic effects that are independent of whether adults meet physical activity guidelines. Evidence from "inactivity physiology" laboratory studies has identified unique mechanisms that are distinct from the biologic bases of exercising… CONTINUE READING