Tonically active NMDA receptors--a signalling mechanism critical for interneuronal excitability in the CA1 stratum radiatum.

Abstract

In contrast to tonic extrasynaptic γ-aminobutyric acid (GABA)A receptor-mediated signalling, the physiological significance of tonic extrasynaptic N-methyl-D-aspartate (NMDA) receptor (NMDAR)-mediated signalling remains uncertain. In this study, reversible open-channel blockers of NMDARs, memantine and phencyclidine (PCP) were used as tools to examine tonic… (More)
DOI: 10.1111/ejn.13128

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@article{Riebe2016TonicallyAN, title={Tonically active NMDA receptors--a signalling mechanism critical for interneuronal excitability in the CA1 stratum radiatum.}, author={Ilse Riebe and Henrik Seth and Georgia R Culley and Zita J Dosa and Shayma Radi and Karin Strand and Victoria Fr{\"o}jd and Eric Allan Hanse}, journal={The European journal of neuroscience}, year={2016}, volume={43 2}, pages={169-78} }