Tonic sympathetic chemoreflex after blockade of respiratory rhythmogenesis in the rat.

@article{Koshiya1996TonicSC,
  title={Tonic sympathetic chemoreflex after blockade of respiratory rhythmogenesis in the rat.},
  author={N Koshiya and Patrice G Guyenet},
  journal={The Journal of physiology},
  year={1996},
  volume={491 ( Pt 3)},
  pages={859-69}
}
1. We sought to determine whether the increase in sympathetic nerve discharge (SND) caused by carotid chemoreceptor stimulation requires the integrity of ventrolateral medullary structures involved in generating respiratory rhythm and pattern. Experiments were done in urethane-anaesthetized, vagotomized, aortic deafferented, ventilated rats except when indicated (see paragraph 3). 2. Brief hypoxia (N2 for 5-12 s) or I.V. NaCN (50-100 micrograms kg-1) activated SND in bursts synchronized with… CONTINUE READING

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