Tonic Dopaminergic Stimulation Impairs Associative Learning in Healthy Subjects

@article{Breitenstein2006TonicDS,
  title={Tonic Dopaminergic Stimulation Impairs Associative Learning in Healthy Subjects},
  author={Caterina Breitenstein and Catharina Korsukewitz and Agnes Fl{\"o}el and Timo Kretzschmar and K. -W. Diederich and Stefan Knecht},
  journal={Neuropsychopharmacology},
  year={2006},
  volume={31},
  pages={2552-2564}
}
Endogenous dopamine plays a central role in salience coding during associative learning. Administration of the dopamine precursor levodopa enhances learning in healthy subjects and stroke patients. Because levodopa increases both phasic and tonic dopaminergic neurotransmission, the critical mechanism mediating the enhancement of learning is unresolved. We here probed how selective tonic dopaminergic stimulation affects associative learning. Forty healthy subjects were trained in a novel… CONTINUE READING
40 Citations
78 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 40 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 78 references

Similar Papers

Loading similar papers…