Tomotherapy PET-guided dose escalation

  title={Tomotherapy PET-guided dose escalation},
  author={Angelo Maggio and Claudia Cutaia and Amalia Di Dia and Sara Bresciani and Anna Miranti and Matteo Poli and Elena Del Mastro and Elisabetta Garibaldi and Pietro Gabriele and Michele Stasi},
  journal={Strahlentherapie und Onkologie},
The aim of this study was to investigate whether a safe escalation of the dose to the pleural cavity and PET/CT-positive areas in patients with unresectable malignant pleural mesothelioma (MPM) is possible using helical tomotherapy (HT). We selected 12 patients with MPM. Three planning strategies were investigated. In the first strategy (standard treatment), treated comprised a prescribed median dose to the planning target volume (PTV) boost (PTV1) of 64.5 Gy (range: 56 Gy/28 fractions to 66 Gy… CONTINUE READING


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