Tomoscintigraphy for detecting gastrointestinal and medullary thyroid cancers: first clinical results using radiolabelled monoclonal antibodies against carcinoembryonic antigen.

@article{Berche1982TomoscintigraphyFD,
  title={Tomoscintigraphy for detecting gastrointestinal and medullary thyroid cancers: first clinical results using radiolabelled monoclonal antibodies against carcinoembryonic antigen.},
  author={C. Berche and Jean Pierre Mach and Jean Daniel J. Lumbroso and Christian Leon August Langlais and Florence Aubry and Franz Buchegger and Stefan Carrel and Philippe Rougier and C. Parmentier and Maurice Tubiana},
  journal={British medical journal},
  year={1982},
  volume={285 6353},
  pages={
          1447-51
        }
}
Transaxial tomoscintigraphy (or single-photon emission computerised tomography) was used to detect secondary deposits of carcinoma in 17 patients who had been injected with iodine-131-labelled monoclonal antibodies against carcinoembryonic antigen. Of 17 tumor sites studied by tomoscintigraphy 16 were detected (sensitivity 94%); five sites had a volume smaller than 10 cm3. Tomoscintigraphy also detected three unknown tumour deposits later confirmed by surgery or radiology. In contrast, when 21… CONTINUE READING
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