Tomato Rab11a characterization evidenced a difference between SYP121-dependent and SYP122-dependent exocytosis.

@article{Rehman2008TomatoRC,
  title={Tomato Rab11a characterization evidenced a difference between SYP121-dependent and SYP122-dependent exocytosis.},
  author={Reiaz Ul Rehman and Egidio Stigliano and Grantley W Lycett and Liliane Sticher and Francesca Sbano and Marianna Faraco and Giuseppe Dalessandro and Gian-Pietro Di Sansebastiano},
  journal={Plant & cell physiology},
  year={2008},
  volume={49 5},
  pages={751-66}
}
The regulatory functions of Rab proteins in membrane trafficking lie in their ability to perform as molecular switches that oscillate between a GTP- and a GDP-bound conformation. The role of tomato LeRab11a in secretion was analyzed in tobacco protoplasts. Green fluorescent protein (GFP)/red fluorescent protein (RFP)-tagged LeRab11a was localized at the trans-Golgi network (TGN) in vivo. Two serines in the GTP-binding site of the protein were mutagenized, giving rise to the three mutants… CONTINUE READING
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